Wellbutrin (bupropion hydrochloride) can it cause permanent tinnitus (even after cessation)?
I was on Zyban (same thing) 150mg for seven days, then stepped up to 300mg for two or three days … I noticed a ringing in my ears (tinnitus) and read the consumer leaflet again and found it to be a rare, but serious side effect to tell your doctor about or go to hospital immediately. Perhaps an exaggeration, but I did stop it the next day. I will be seeing my doctor in less than two weeks; however his opinion may be bias.
The problem is … it’s been a couple of days and it hasn’t gone away. An incessant ringing in my ears that varies with intensity. Not a problem that I’ve had before which is an important consideration.
Questions are, how (mechanism of action) does is cause this? I also recall feeling a popping sensation in my left ear that night, could this be related or a sign of damage?
Why is it considered such a serious side effect? (i.e., they don’t list it as a side effect that you can ignore and only tell your doctor about if it becomes bothersome)
And finally (I wasn’t warned about this!) but can it possibly be permanent?
I was told to up the dosage after 3-7 days depending on tolerability … thought it was obvious.
Tagged with: bias • couple of days • exaggeration • intensity • leaflet • left ear • mechanism of action • ringing in my ears • sensation • seven days • tinnitus
Filed under: Ear Noise


I had some tinnitus during and after using Wellbutrin but it did go away after a week or two. From what I understand it’s a common side effect.
Try splitting the dose. That may do away with the side effects.
Did you change your dose without doc instructions to do so, and then stop it all together without talking to your doc?? With that kind of self treatment, you are setting yourself up for problems. Call your doc mon, and then actually follow the instructions given to you. Why did you up your dosage in the first place??? You do realize this is a slow process and like every other anti depressant, it can take up to 4-6 weeks to notice a difference.